Recombinant Ranpirnase enhances the expression of co-transfected mRNA by modulating cellular metabolic activity
Xiujin Wu, Chen Liang, Yingxue Lei, Peng Xu, Yaoyi Zhang, Guang Yang, Hailin Yin, Kai Xu
This study shows that recombinant Ranpirnase enhances mRNA transgene expression in mice by 3-6 fold and prolongs its duration by over 85% without cytotoxicity.
bioRxiv · Jul 22, 2023 · PreprintMolecular Biology