Author

Hailin Yin

Sichuan University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Assay:multiome· 2 Research Focus:differential expression· 1 Organism:rat· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Kai XuiD· 3 shared Guang YangiD· 2 shared Xiujin WuiD· 2 shared Yaoyi ZhangiD· 2 shared Yingxue Lei· 2 shared Binghe XuiD· 1 shared Chen HeiD· 1 shared Chen LiangiD· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersMolecular Biology

Kai XuORCID

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3 papers

Recent·Most cited

Recombinant Ranpirnase enhances the expression of co-transfected mRNA by modulating cellular metabolic activity

Xiujin Wu, Chen Liang, Yingxue Lei, Peng Xu, Yaoyi Zhang, Guang Yang, Hailin Yin, Kai Xu

This study shows that recombinant Ranpirnase enhances mRNA transgene expression in mice by 3-6 fold and prolongs its duration by over 85% without cytotoxicity.

bioRxiv · Jul 22, 2023 · PreprintMolecular Biology

Improving mRNA vaccine safety and efficiency with cationized lipid nanoparticle formula

Peng Xu, Guangneng Liao, Dongsheng Ren, Yucheng Zhou, Xiujin Wu, Yingxue Lei, Yan Zhang, Liang Chen, Chen He, Yaoyi Zhang, Hailin Yin, Guang Yang, Kai Xu

This study modifies an mRNA-LNP vaccine formula with a cationic lipid to improve safety and efficiency, showing better immunogenicity and reduced off-target effects in mice.

bioRxiv · Mar 29, 2023 · PreprintSynthetic Biology

The plasma miR-122 basal levels respond to circulating catecholamine in rats

Peng Xu, Qiao Li, Song Lu, Xueling He, Sisi Yu, Zhihui Zhang, Guohui Xu, Li Lu, Tinghan Yang, Jiang Zhu, Wenli Zhu, Zhigang Wu, Delun Luo, Jie Zhu, Binghe Xu, , Kai Xu

This study shows that plasma miR-122 levels in rats are influenced by circulating catecholamines and stress, suggesting a non-hepatic source for miR-122 release.

bioRxiv · Jan 31, 2018 · PreprintMolecular Biology