Author

Yaoyi Zhang

ORCID 0000-0001-6362-3422Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Assay:multiome· 2 Research Focus:differential expression· 1 Research Focus:spatial domain detection· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Guang YangiD· 2 shared Hailin Yin· 2 shared Kai XuiD· 2 shared Xiujin WuiD· 2 shared Yingxue Lei· 2 shared Chen HeiD· 1 shared Chen LiangiD· 1 shared Dongsheng ReniD· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersMolecular Biology

Guang YangORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintJul 22, 2023

Recombinant Ranpirnase enhances the expression of co-transfected mRNA by modulating cellular metabolic activity

Xiujin Wu, Chen Liang, Yingxue Lei…·Kai Xu

This study shows that recombinant Ranpirnase enhances mRNA transgene expression in mice by 3-6 fold and prolongs its duration by over 85% without cytotoxicity.

DOI 10.1101/2023.07.22.550185

mousemultiome

𝕏 PostBluesky

Synthetic BiologybioRxivPreprintMar 29, 2023

Improving mRNA vaccine safety and efficiency with cationized lipid nanoparticle formula

Peng Xu, Guangneng Liao, Dongsheng Ren…·Kai Xu

This study modifies an mRNA-LNP vaccine formula with a cationic lipid to improve safety and efficiency, showing better immunogenicity and reduced off-target effects in mice.

4 citations

mousemultiome

𝕏 PostBluesky