Guang Yang

This study shows that recombinant Ranpirnase enhances mRNA transgene expression in mice by 3-6 fold and prolongs its duration by over 85% without cytotoxicity.

This study modifies an mRNA-LNP vaccine formula with a cationic lipid to improve safety and efficiency, showing better immunogenicity and reduced off-target effects in mice.

The study uses nanopore sequencing to analyze structural variations in rhesus macaques, finding more SVs on the X chromosome and evidence of positive selection.