BiochemistryNature Structural & Molecular BiologyPeer-reviewed
Structure and function of the yeast amino acid-sensing SEAC-EGOC supercomplex
Lucas Tafur, Lenny Bonadei, Yiqiang Zheng…·Robbie Loewith
This study determines the cryo-EM structure of the SEAC-EGOC supercomplex in yeast and shows its role in amino acid signaling to TORC1, revealing how SEACIT and SEACAT regulate this process.