Author

Yoko Oguchi

Heidelberg University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Frank Zimmermann· 1 shared Joachim WittbrodtiD· 1 shared Marc FreicheliD· 1 shared Rebekka MedertiD· 1 shared Sascha Dlugosz· 1 shared Tanja Kellner· 1 shared Thomas ThumbergeriD· 1 shared Tinatini TavhelidseiD· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperMolecular Biology

Frank Zimmermann

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1 paper

Recent·Most cited

Efficient single copy integration via homology-directed repair (scHDR) by 5'modification of large DNA donor fragments in mice

Rebekka Medert, Thomas Thumberger, Tinatini Tavhelidse, Tobias Hub, Tanja Kellner, Yoko Oguchi, Sascha Dlugosz, Frank Zimmermann, Joachim Wittbrodt, Marc Freichel

This study demonstrates that 5-biotinylation of donor DNA enhances single-copy HDR in mice, achieving 19-26% efficiency in generating conditional alleles.

Nucleic Acids Research · Dec 12, 2022Peer-reviewedMolecular Biology