Author

Tanja Kellner

Heidelberg University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Assay:CRISPR screen· 1 Organism:mouse· 1 Research Focus:variant calling· 1 Organism:zebrafish· 1

Frequent Co-Authors

Joachim WittbrodtiD· 2 shared Thomas ThumbergeriD· 2 shared Tinatini TavhelidseiD· 2 shared Beate WittbrodtiD· 1 shared Erika TsingosiD· 1 shared Frank Zimmermann· 1 shared Isabelle Thomas· 1 shared José Arturo Gutierrez-Triana· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMolecular Biology

Joachim WittbrodtORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Efficient single copy integration via homology-directed repair (scHDR) by 5'modification of large DNA donor fragments in mice

Rebekka Medert, Thomas Thumberger, Tinatini Tavhelidse, Tobias Hub, Tanja Kellner, Yoko Oguchi, Sascha Dlugosz, Frank Zimmermann, Joachim Wittbrodt, Marc Freichel

This study demonstrates that 5-biotinylation of donor DNA enhances single-copy HDR in mice, achieving 19-26% efficiency in generating conditional alleles.

Nucleic Acids Research · Dec 12, 2022Peer-reviewedMolecular Biology

Efficient single-copy HDR by 5’ modified long dsDNA donors

José Arturo Gutierrez-Triana, Tinatini Tavhelidse, Thomas Thumberger, Isabelle Thomas, Beate Wittbrodt, Tanja Kellner, Kerim Anlaş, Erika Tsingos, Joachim Wittbrodt

The paper demonstrates that modifying the 5' ends of long dsDNA donors enhances HDR efficiency in Medaka, enabling efficient single-copy integration through monomeric donor conformation.

eLife · Aug 20, 2018Peer-reviewedGenetics