Author

Yong-Hao Li

Tongji University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:C. elegans· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Fang-Lin SuniD· 2 shared Yuanya Jing· 2 shared Chen WangiD· 1 shared Chen Wang· 1 shared Cizhong JiangiD· 1 shared Dan Peng· 1 shared Feng SuniD· 1 shared Haowei WangiD· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersGenetics

Fang-Lin SunORCID

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2 papers

Recent·Most cited

The spreading of facultative H3K9me3-heterochromatin drives congenital disease

Chen Wang, Wei Zhang, Xuelin Chen, Wenfei Wang, Yong-Hao Li, Jian-Feng Chang, Xiao-Bo Guo, Yuanya Jing, Yabin Li, Xinyi Lu, Yutong Li, Kai Liu, Jian‐Quan Ni, Fang-Lin Sun

This study identifies Cdk13's role in preventing H3K9me3-heterochromatin spreading, which causes congenital heart defects, and shows a compound can alleviate these defects in mice.

bioRxiv · Aug 11, 2023 · PreprintGenetics

The Establishment of Transgenerational Epigenetic Inheritance in the C. elegans Germline is Mediated by Lipid Metabolism

Dan Peng, Chen Wang, Kai-Le Li, Zhixue Gan, Yong-Hao Li, Haowei Wang, Qiuyu Li, Xiwei Liu, He-Yuan Sun, Yuanya Jing, Qiang Fang, Qian Zhao, Lei Zhang, Huanhuan Chen, Hui-Min Wei, , Fang-Lin Sun

This study shows that lipid metabolism, via Pod-2 and vitellogenins, mediates the establishment of transgenerational epigenetic imprints in C. elegans germline.

bioRxiv · Nov 4, 2020 · PreprintGenetics