Karina Yaniv

This study reconstructs mouse vasculogenesis using single-cell and spatial analyses, revealing a transient vascular-primed state and the role of VEGF in endothelial specification.

This study identifies conserved and divergent developmental programs for cerebellar output neurons in zebrafish, showing shared origins with other vertebrates and unique mechanisms for eurydendroid cell organization.

This study identifies ferroptosis as a regulator of lymphatic vessel growth and regression, showing its role in development and injury response through metabolic and lipid pathway mechanisms.

This study identifies and characterizes circulating endothelial cells (CECs) using single-cell data, revealing their diverse origins and plasticity, and links them to angiogenic programs in cancer.

This study identifies potential treatments for Kaposiform Lymphangiomatosis using a zebrafish model and high-throughput drug screening.

This study identifies a conserved venous remodeling program in zebrafish that mirrors mammalian IVC formation, revealing cellular origins and molecular mechanisms of IVC development.

This study identifies endolysosomal dysfunction in radial glia progenitor cells as a cause of defective cerebral angiogenesis and BBB compromise in zebrafish, linking Notch3 processing defects to CSVD phenotypes.

This study creates zebrafish mutants to study Apolipoprotein B's role in development and disease, finding defects in lipid metabolism and vascular development.

This study shows that VEGFC induces cell-cycle arrest in endothelial cells, promoting sprouting and differentiation in venous and lymphatic vessels.

This study shows that lymphatic endothelial cells can transdifferentiate into blood vessel endothelial cells in zebrafish, linking cell origin to function in vascular development and regeneration.

This study identifies BACH family members as regulators of VEGFC expression, impacting angiogenesis and lymphangiogenesis in zebrafish and mouse models.