Jacob Elkahal

The paper uses spatial transcriptomics to analyze thyroid heterogeneity, identifying a damage-response thyrocyte state that balances with hormone-producing states across scales.

This study identifies and characterizes circulating endothelial cells (CECs) using single-cell data, revealing their diverse origins and plasticity, and links them to angiogenic programs in cancer.

The paper identifies a cold fibrotic network in LUSC TME driven by CAFs and shows its conservation in other CIACs, suggesting therapeutic targets.

The paper models a macrophage-myofibroblast circuit to predict fibrosis types and shows targeting the myofibroblast autocrine loop reduces fibrosis after myocardial infarction.