Xiaoyang Wu

This study shows that FAK activation drives PAO-induced skin injury by disrupting focal adhesions, and inhibiting FAK protects against vesicant-induced damage.

This study shows that METTL14-dependent m6A modification prevents myocarditis and dilated cardiomyopathy by restraining IFN signaling and necroptosis in cardiomyocytes.

This paper demonstrates a method using engineered piggyBac transposase and CRISPR/Cas9 to achieve targeted integration of large DNA fragments into the human genome with high specificity and efficiency.

The paper reports the cryo-EM structure of full sACE dimer and uses MD simulations to study its conformational dynamics and domain-specific behavior.

This study shows MACF1 is essential for bone formation by enabling SMAD7 nuclear translocation in MSCs, leading to ossification retardation and bone loss in mice.

The paper develops a CRISPR-mediated skin sensor for continuous blood glucose monitoring and diabetes treatment using genome-edited epidermal stem cells.