Author

Yu-Qing Zhou

Hospital for Sick Children

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1

Frequent Co-Authors

Aliya IzumiiD· 1 shared Anthony O GramoliniiD· 1 shared Benoit G. BruneauiD· 1 shared Boris Hinz· 1 shared Carol C. GregorioiD· 1 shared Christine E. SeidmaniD· 1 shared Cristine J ReitziD· 1 shared Danos C. Christodoulou· 1 shared

Activity by Year

2017-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperPhysiology

Aliya IzumiORCID

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2 papers

Recent·Most cited

Latent Transforming Growth Factor Binding Protein-2 promotes microfibrillar TGF-β bioavailability to drive pathologic fibrosis in remote regions of infarcted hearts

Fahad Ehsan, Michelle Di Paola, Micael Dewar, Hangjun Zhang, Uros Kuzmanov, Yu-Qing Zhou, Cristine J Reitz, Haisam Shah, Tao Wang, Jingzhi Liu, Aliya Izumi, Rundong Hu, Joanna Hendy, Fareshteh Sadat Younesi, Mark K. Friedberg, , Scott P Heximer

This study shows that LTBP2 promotes fibrosis in remote myocardium after MI by sequestering latent TGF-β, and its deletion reduces fibrosis and improves cardiac function.

bioRxiv · Nov 3, 2026 · PreprintPhysiology

Cardiac enriched BAF chromatin remodeling complex subunit Baf60c regulates gene expression programs essential for heart development and function

Xin Sun, Swetansu K. Hota, Yu-Qing Zhou, Stefanie Mares Novak, Dario Miguel-Perez, Danos C. Christodoulou, Christine E. Seidman, Jonathan G. Seidman, Carol C. Gregorio, R. Mark Henkelman, Janet Rossant, Benoit G. Bruneau

This study shows that Baf60c regulates gene expression programs critical for heart development and function by interacting with Myocardin and controlling contractile proteins and metabolic genes.

Biology Open · Jan 1, 2017Peer-reviewedDevelopmental Biology