Author

Yuanyue Zhou

Sangamo BioSciences (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:CITE-seq· 1 Assay:CRISPR screen· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Andreas Reik· 2 shared Lynn N. Truong· 2 shared Adeline Chen· 1 shared Andrew NguyeniD· 1 shared Angélique E. Martelli· 1 shared Bhakti N Kadam· 1 shared Bryan Bourgeois· 1 shared Caroline Jeanneau· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

Andreas Reik

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Author profile →

2 papers

Recent·Most cited

Enhanced anti-tumor activity by Zinc Finger Repressor-driven epigenetic silencing of immune checkpoints and TGFBR2 in CAR-T cells and TILs

Marion David, Phillip Schiele, Davide Monteferrario, Gaëlle Saviane, Angélique E. Martelli, Coralie F Dupont, Caroline Jeanneau, Irène Marchetti, Satish Kumar Tadi, Julia Vahldick, Lynn N. Truong, Yuanyue Zhou, Igor Maximilian Sauer, Wenzel Schöning, Il‐Kang Na, , David Fenard

This paper enhances CAR-T cell and TIL anti-tumor activity by epigenetically silencing immune checkpoints and TGFBR2 using Zinc Finger Repressors.

Molecular Therapy Oncology · May 7, 2025Peer-reviewedCancer Biology

Reprogrammed Serine Integrases Enable Precise Integration of Synthetic DNA

Friedrich Fauser, Sebastian Arangundy‐Franklin, Jessica E. Davis, Lifeng Liu, Nicola J Schmidt, Luis Rodriguez, Danny F. Xia, Nga Nguyen, Nicholas A. Scarlott, Rakshaa Mureli, Irene Tan, Yuanyue Zhou, Lynn N. Truong, Sarah J Hinkley, Bhakti N Kadam, , Jeffrey C. Miller

The paper develops a MINT platform to reprogram serine integrases for precise synthetic DNA integration into specific chromosomal sites in human cells.

bioRxiv · May 9, 2024 · PreprintSynthetic Biology