Author

Yue A. Qi

National Institutes of Health

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Assay:CRISPR screen· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:perturbation response prediction· 1 Research Focus:software / tool· 1 Approach:statistical model· 1

Frequent Co-Authors

Jacob EpsteiniD· 2 shared Michael Emmerson WardiD· 2 shared Mike A. NallsiD· 2 shared Ziyi Li· 2 shared Andrea MalaspinaiD· 1 shared Anna‐Leigh BrowniD· 1 shared Ariana P. GattiD· 1 shared Ashirwad MerveiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersBioinformatics

Jacob EpsteinORCID

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Author profile →

3 papers

Recent·Most cited

ProtPipe2: Multi-Platform Downstream Proteomics Analysis Tool

Jacob Epstein, Cory A. Weller, Isabelle Kowal, Ying Hao, Cole Tindall, Benjamin Jin, Mark Cookson, Mike A. Nalls, Ziyi Li, Yue A. Qi

ProtPipe2 provides a unified framework for downstream proteomics analysis across mass spectrometry, Olink, and SomaScan platforms, enabling consistent workflows and reusable analyses.

bioRxiv · Sep 21, 2026 · PreprintBioinformatics

Maintenance of neuronal TDP-43 expression requires axonal lysosome transport

Veronica H. Ryan, Sydney Lawton, Joel F. Reyes, James Hawrot, Ashley M. Frankenfield, Sahba Seddighi, Daniel M. Ramos, Jacob Epstein, Faraz Faghri, Nicholas L. Johnson, Jizhong Zou, Martin Kampmann, John Michael Replogle, Yue A. Qi, Hebao Yuan, , Michael Emmerson Ward

The paper identifies BORC as a modifier of TDP-43 protein levels in neurons, showing lysosome transport is required for TDP-43 turnover.

eLife · Sep 1, 2025Peer-reviewedNeuroscience

TDP-43 pathology induces CD8+ T cell activation through cryptic epitope recognition

Shahab Chizari, Matteo Zanovello, Steven Lingyang Kong, Vidur J. Saigal, Anna‐Leigh Brown, Valentina Turchetti, Bingxian Chen, Connor C. Devine, Luca Zampedri, Iwona Skorupinska, Giacomo Maria Minicuci, Francesca Paron, Paola Tonin, Giulia Marchetto, Ziyi Li, , Ning Jenny Jiang

This study identifies cryptic epitopes from de novo proteins caused by TDP-43 pathology as targets of CD8+ T cell activation in ALS and IBM.

bioRxiv · Jun 22, 2025 · PreprintImmunology