Author

Yuelian Zhu

University of California San Diego

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Approach:statistical model· 1

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Jeff HastyiD· 1 shared Julie PaxmaniD· 1 shared Lev S. TsimringiD· 1 shared Lorraine PillusiD· 1 shared Nan HaoiD· 1 shared Richard O’LaughliniD· 1 shared Stephen KlepiniD· 1 shared Yanfei JiangiD· 1 shared

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Jeff HastyORCID

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1 paper

Recent·Most cited

An epigenetic landscape governs early fate decision in cellular aging

Yang Li, Yanfei Jiang, Julie Paxman, Richard O’Laughlin, Stephen Klepin, Yuelian Zhu, Lorraine Pillus, Lev S. Tsimring, Jeff Hasty, Nan Hao

The paper shows that interactions between chromatin silencing and mitochondrial pathways create an epigenetic landscape that determines cell fate during aging, and introduces a genetically engineered long-lived state.

Science · Jul 17, 2020Peer-reviewedSystems Biology