Yanfei Jiang

The paper investigates how type I interferon signaling in human epithelial cells processes repetitive stimulation through cell cycle-gated feedback control, revealing duration-dependent desensitization.

The paper shows that interactions between chromatin silencing and mitochondrial pathways create an epigenetic landscape that determines cell fate during aging, and introduces a genetically engineered long-lived state.

The paper investigates how yeast cells encode short- and long-lived memory of stress adaptation through PKA-regulated networks and trehalose metabolism.