Author

Yufan Xie

Shanghai Jiao Tong University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:deep learning· 2 Assay:DNA methylation· 1 Assay:electronic health records· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Guojun HouiD· 1 shared Haiyan Huang· 1 shared Haizhao DaiiD· 1 shared Huaijin Feng· 1 shared Jiakai ZhangiD· 1 shared Jin ZhuiD· 1 shared Jingjing ZhengiD· 1 shared Jingyi Yu AiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperGenomics

Guojun HouORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cryo-EM as latent structural landscape microscopy

Haizhao Dai, Qihe Chen, Lingqi Li, Yingjun Shen, Zhenyang Xu, Minzhang Li, Yufan Xie, Jingjing Zheng, Zhi‐Jie Liu, Liping Sun, Yuan Pei, Jiakai Zhang, Jingyi Yu A

This paper introduces a method to analyze cryo-EM data as continuous structural landscapes, revealing molecular dynamics and previously unresolved states.

bioRxiv · Apr 17, 2026 · PreprintMolecular Biology

DNA sequence quantitatively encodes CTCF-binding affinity at genome scale

Zihang Yin, Yefan Wang, Guojun Hou, Yuqiao Chen, Huaijin Feng, Jin Zhu, Yufan Xie, Ruoxi Wang, Zhiyu Zhang, Tao Wu, Haiyan Huang, Sheila Q. Xie, Wuming Wang, Wenchao Gu, Qiang Wu, , Ya Guo

The paper experimentally measures CTCF-binding affinity across 276,765 human DNA sequences and develops a deep learning model to predict and interpret binding strength based on sequence features.

bioRxiv · Jan 5, 2026 · PreprintGenomics