Author

Yuko Hirata

The University of Tokyo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Adam P GiessiD· 1 shared Afshan SiddiqiD· 1 shared Akihiro NakadaiD· 1 shared Alessio MasiiD· 1 shared Alexander SieghartiD· 1 shared Alexander StuckeyiD· 1 shared Alona SosinskyiD· 1 shared Ana Lisa Taylor TavaresiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Adam P GiessORCID

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2 papers

Recent·Most cited

Enzyme activity as an actionable axis for small-molecule precision oncology

Kyohhei Fujita, Mako Kamiya, Shingo Dan, Ryo Tachibana, Minoru Kawatani, Ryosuke Kojima, Rumi Hino, Kimihiko Kobayashi, Shotaro Inoue, Miyuki Tani, Yuko Hirata, Shun Kawashima, Kanami Yamazaki, Yumiko H. Nishimura, Yoshimi Ohashi, , Yasuteru Urano

This paper develops enzyme activity-based prodrugs for precision oncology, showing reduced toxicity and improved efficacy in tumor models.

bioRxiv · Apr 15, 2026 · PreprintCancer Biology

Stretch-activated ion channel TMEM63B associates with developmental and epileptic encephalopathies and progressive neurodegeneration

Annalisa Vetro, Cristiana Pelorosso, Simona Balestrini, Alessio Masi, Sophie Hambleton, Emanuela Argilli, Valerio Conti, Simone Giubbolini, Rebekah Barrick, Gaber Bergant, Karin Writzl, Emilia K. Bijlsma, Theresa Brunet, Pilar Cacheiro, Davide Mei, , Ellen Thomas

This study identifies TMEM63B variants in patients with developmental and epileptic encephalopathy and neurodegeneration, showing altered cation currents and hematological abnormalities.

The American Journal of Human Genetics · Jul 7, 2023Peer-reviewedGenetic & Genomic Medicine