Subventricular zone adult mouse neural stem cells and human glioblastoma stem cells require insulin receptor for self-renewal
Shravanthi Chidambaram, Deborah E. Rothbard, Kaivalya S Deshpande, Yvelanda Cajuste, Kristin M. Snyder, Eduardo J. Fajardo, András Fiser, Nikos Tapinos, Steven W. Levison, Teresa L. Wood
This study shows that the insulin receptor is essential for maintaining adult neural stem cells and inhibiting glioblastoma stem cell self-renewal.
bioRxiv · Mar 10, 2020 · PreprintNeuroscience