Steven W. Levison

This study uses human brain organoids to show that transient IL-6 exposure during prenatal development disrupts interneuron maturation and subtype specification, linking it to neurodevelopmental disorders.

The paper identifies unique molecular subtypes of transit amplifying neural progenitors in the neonatal mouse subventricular zone using RNASeq and bioinformatics.

This study shows that intranasal LIF treatment reduces delayed neurodegeneration and improves sensorimotor function after mild traumatic brain injury.

This study shows that increasing IL-6 levels during postnatal neurogenesis disrupts brain development and leads to behavioral deficits in mice.

The paper shows that inducing autophagy after perinatal hypoxia-ischemia reduces cell death and improves neurological outcomes in rats.

This study shows that low oxygen levels promote proliferation of mouse oligodendrocyte progenitors, unlike rat OPCs, and identifies factors affecting their differentiation.

The paper investigates how LIF deficiency affects oligodendrocyte progenitor cell proliferation after traumatic brain injury in mice, finding increased proliferation in LIF heterozygous mice.

This study shows that perinatal IL-1-induced inflammation reduces Tbr2+ progenitor cell proliferation in the hippocampus, leading to long-term anxiety and spatial memory deficits in mice.

This study shows that the insulin receptor is essential for maintaining adult neural stem cells and inhibiting glioblastoma stem cell self-renewal.