András Fiser

The paper develops a structure prediction method using XL-MS data for disordered microsporidian proteins with no homologs, successfully modeling two spore wall proteins.

This study shows that inhibiting HDAC7 alters H3.3 deposition and chromatin structure, leading to DNA replication defects and increased sensitivity to DNA damage in cancer cells.

The paper introduces ISPIPab, a program that predicts multiple antigen epitopes by combining feature-based and docking-based methods, outperforming existing approaches and revealing novel targets.

This study evaluates how different protein binding site definitions affect ligand recognition using a pharmacophore approach, providing a guideline for minimum interface definition accuracy.

The paper identifies a functional variant in the 9p21.3 locus associated with glaucoma risk and shows it increases p16INK4a expression by disrupting YY1 binding.

This study shows that the EGR2 promoter antisense RNA modulates chromatin accessibility and spatial genome organization by interacting with histone modification complexes.

This study shows that the insulin receptor is essential for maintaining adult neural stem cells and inhibiting glioblastoma stem cell self-renewal.