Nikos Tapinos

This study combines long-read RNA sequencing and polysome profiling to show that transposable elements drive transcript diversity and alter translation in glioblastoma stem cells.

This study shows that inhibiting HDAC7 alters H3.3 deposition and chromatin structure, leading to DNA replication defects and increased sensitivity to DNA damage in cancer cells.

This study profiles hypoxic glioblastoma stem cells using multi-omics to reveal distinct subpopulations with unique epigenetic and CNV profiles.

This study shows that the EGR2 promoter antisense RNA modulates chromatin accessibility and spatial genome organization by interacting with histone modification complexes.

This study shows that the insulin receptor is essential for maintaining adult neural stem cells and inhibiting glioblastoma stem cell self-renewal.