Inflammasome-independent role for NLRP3 in controlling innate anti-helminth immunity and tissue repair in the lung
A. Chenery, R. Alhallaf, Z. Agha, J. Ajendra, J. Parkinson, M. M. Cooper, B. H. Chan, R. M. Eichenberger, L. A. Dent, A. A. Robertson, A. Kupz, D. Brough, A. Loukas, T. E. Sutherland, J. E. Allen, P. Giacomin
This study shows NLRP3 limits lung neutrophilia and helminth killing in an inflammasome-independent way, while promoting tissue repair.
bioRxiv · Jun 7, 2019Immunology