Dysregulated Pulmonary Inflammatory Responses Exacerbate the Outcome of Secondary Aspergillosis Following Influenza
C. K. Lee, L. V. N. Oliveira, A. Akalin, C. Specht, D. Lourenco, C. L. Gomez, Z. G. Ramirez-Ortiz, J. P. Wang, S. M. Levitz
This study shows that superinfected mice with influenza and Aspergillus fumigatus have higher mortality during early influenza stages due to dysregulated inflammation, not increased fungal growth.
bioRxiv · Jun 27, 2023Immunology