Author

J. P. Wang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1

Frequent Co-Authors

R. W. Finberg· 4 shared M. Somasundaran· 2 shared P. Liu· 2 shared A. Akalin· 1 shared A. Cousineau· 1 shared A. L. Brass· 1 shared A. L. Gard· 1 shared B. C. Isenberg· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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4 shared papersMicrobiology

R. W. Finberg

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Dysregulated Pulmonary Inflammatory Responses Exacerbate the Outcome of Secondary Aspergillosis Following Influenza

C. K. Lee, L. V. N. Oliveira, A. Akalin, C. Specht, D. Lourenco, C. L. Gomez, Z. G. Ramirez-Ortiz, J. P. Wang, S. M. Levitz

This study shows that superinfected mice with influenza and Aspergillus fumigatus have higher mortality during early influenza stages due to dysregulated inflammation, not increased fungal growth.

bioRxiv · Jun 27, 2023Immunology

Cell culture model system utilizing engineered A549 cells to express high levels of ACE2 and TMPRSS2 for investigating SARS-CoV-2 infection and antivirals

C.-W. Chang, K. M. Parsi, M. Somasundaran, E. Vanderleeden, J. Cruz, A. Cousineau, P. Liu, Q. Li, Y. Wang, R. Maehr, J. P. Wang, R. W. Finberg

This paper develops an engineered A549 cell model overexpressing ACE2 and TMPRSS2 to study SARS-CoV-2 infection and antiviral responses.

bioRxiv · Dec 31, 2021Cell Biology

Quantitative Structural Analysis of Influenza Virus by Cryo-electron Tomography and Convolutional Neural Networks

Q. Y. Huang, K. Song, C. Xu, D. Bolon, J. P. Wang, R. W. Finberg, C. A. Schiffer, M. Somasundaran

This paper develops a cryoET processing pipeline using CNNs to characterize the morphology and structure of influenza viruses, improving analysis throughput and enabling subtomogram averaging of glycoproteins.

bioRxiv · Dec 9, 2021Microbiology

High-Throughput Human Primary Cell-Based Airway Model for Evaluating Influenza, Coronavirus, or other Respiratory Viruses in vitro

A. L. Gard, R. Maloney, B. P. Cain, C. R. Miller, R. J. Luu, J. R. Coppeta, P. Liu, J. P. Wang, H. Azizgolshani, R. F. Fezzie, J. L. Balestrini, B. C. Isenberg, R. W. Finberg, J. T. Borenstein

This paper introduces a human primary airway epithelial cell-based model for evaluating influenza and coronavirus infections in vitro, demonstrating its ability to assess viral infection kinetics and therapeutic efficacy.

bioRxiv · May 23, 2020Microbiology

Identification of A Disintegrin and Metalloproteinase 9 domain (ADAM9) required in the early stages of encephalomyocarditis virus infection

L. E. Bazzone, M. King, C. R. MacKay, P. P. Kyawe, P. Meraner, D. Lindstrom, J. Rojas-Quintero, C. A. Owen, J. P. Wang, A. L. Brass, E. A. Kurt-Jones, R. W. Finberg

This study identifies ADAM9 as a host factor required for early stages of EMCV infection using CRISPR-Cas9 screening, showing resistance in ADAM9 knockout cells.

bioRxiv · Dec 9, 2018Microbiology