Author

S. M. Levitz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:mouse· 3 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Organism:fungi (other)· 1

Frequent Co-Authors

C. Specht· 3 shared C. K. Lee· 2 shared C. L. Gomez· 2 shared L. V. N. Oliveira· 2 shared M. M. Hester· 2 shared A. Abraham· 1 shared A. Akalin· 1 shared A. E. Ragsdale· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersImmunology

C. Specht

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Author profile →

4 papers

Recent·Most cited

Protection against experimental cryptococcosis elicited by Cationic Adjuvant Formulation 01-adjuvanted subunit vaccines

R. Wang, L. V. N. Oliveira, M. M. Hester, D. M. Carlson, D. Christensen, C. A. Specht, S. M. Levitz

This paper develops multivalent cryptococcal vaccines using CAF01 adjuvant that protect mice from experimental cryptococcosis by inducing IFNγ and IL-17 responses.

bioRxiv · Apr 24, 2024 · PreprintImmunology

Dysregulated Pulmonary Inflammatory Responses Exacerbate the Outcome of Secondary Aspergillosis Following Influenza

C. K. Lee, L. V. N. Oliveira, A. Akalin, C. Specht, D. Lourenco, C. L. Gomez, Z. G. Ramirez-Ortiz, J. P. Wang, S. M. Levitz

This study shows that superinfected mice with influenza and Aspergillus fumigatus have higher mortality during early influenza stages due to dysregulated inflammation, not increased fungal growth.

bioRxiv · Jun 27, 2023Immunology

Protection of mice against experimental cryptococcosis by synthesized peptides delivered in glucan particles

C. Specht, E. J. Homan, C. K. Lee, Z. Mou, C. L. Gomez, M. M. Hester, A. Abraham, F. Rus, G. Ostroff, S. M. Levitz

The paper shows that glucan particle-based vaccines containing specific peptides from C. neoformans proteins can protect mice against cryptococcosis, with varying efficacy depending on the peptide and mouse strain.

bioRxiv · Nov 12, 2021Immunology

Chitosan biosynthesis and virulence in the human fungal pathogen Cryptococcus gattii

W. C. Lam, R. Upadhya, C. Specht, A. E. Ragsdale, C. R. Hole, S. M. Levitz, J. K. Lodge

This study shows that C. gattii R265 has higher chitosan in its cell wall and that CDA3 is critical for its virulence, with CDA deletions making it avirulent.

mSphere · Oct 30, 2019Peer-reviewedMicrobiology