Activated I-BAR IRSp53 clustering controls the formation of VASP-actin-based membrane protrusions
F.-C. Tsai, J. M. Henderson, Z. Jarin, E. Kremneva, Y. Senju, J. Pernier, O. Mikhajlov, J. Manzi, K. Kogan, C. Le Clainche, G. A. Voth, P. Lappalainen, P. Bassereau
The paper investigates how IRSp53 clustering regulates filopodia initiation by recruiting VASP to form actin-based membrane protrusions.
bioRxiv · Mar 4, 2022Biophysics