Author

E. Kremneva

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 5 Research Focus:development & morphogenesis· 3 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1

Frequent Co-Authors

P. Lappalainen· 4 shared J. Ivaska· 2 shared K. Kogan· 2 shared A. Isomursu· 1 shared C. Le Clainche· 1 shared E. Bertling· 1 shared E. Ruusuvuori· 1 shared E. T. Coffey· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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4 shared papersCell Biology

P. Lappalainen

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Author profile →

5 papers

Recent·Most cited

Specialized actin nanoscale layers control focal adhesion turnover

R. Kumari, K. Ven, M. Chastney, J. Peranen, J. Arron, L. Almeida-Souza, E. Kremneva, R. Poincloux, T. L. Chew, P. W. Gunning, J. Ivaska, P. Lappalainen

The paper identifies two new nanoscale actin layers in focal adhesions, showing their distinct roles in adhesion maturation and disassembly through Tpm1.6 and Tpm3.2.

bioRxiv · Feb 15, 2023 · PreprintCell Biology

Structural basis underlying specific biochemical activities of non-muscle tropomyosin isoforms

M. Selvaraj, S. Kokate, G. Reggiano, K. Kogan, T. Kotila, E. Kremneva, F. DiMaio, P. Lappalainen, J. T. Huiskonen

The paper determines cryo-EM structures of actin filaments with two non-muscle tropomyosin isoforms, revealing structural differences that explain their distinct functional roles.

bioRxiv · May 12, 2022Biochemistry

Activated I-BAR IRSp53 clustering controls the formation of VASP-actin-based membrane protrusions

F.-C. Tsai, J. M. Henderson, Z. Jarin, E. Kremneva, Y. Senju, J. Pernier, O. Mikhajlov, J. Manzi, K. Kogan, C. Le Clainche, G. A. Voth, P. Lappalainen, P. Bassereau

The paper investigates how IRSp53 clustering regulates filopodia initiation by recruiting VASP to form actin-based membrane protrusions.

bioRxiv · Mar 4, 2022Biophysics

Conformational dynamics regulate SHANK3 actin and Rap1 binding

S. I. Salomaa, M. Miihkinen, E. Kremneva, I. Paatero, J. Lilja, G. Jacquemet, J. Vuorio, L. Antenucci, F. Hassani-Nia, P. Hollos, A. Isomursu, I. Vattulainen, E. T. Coffey, H.-J. Kreienkamp, P. Lappalainen, J. Ivaska

This study shows SHANK3 binds actin and Rap1 through its SPN domain, with conformational changes regulating this interaction and affecting cellular processes like filopodia formation and autism-related phenotypes.

bioRxiv · Nov 12, 2020 · PreprintCell Biology

Carbonic anhydrase VII regulates dendritic spine morphology and density via actin filament bundling

E. Bertling, P. Blaesse, P. Seja, E. Kremneva, G. Gateva, M. A. Virtanen, M. Summanen, I. Spoljaric, M. Blaesse, V. Paavilainen, L. Vutskits, K. Kaila, P. Hotulainen, E. Ruusuvuori

This study shows that CAVII regulates dendritic spine morphology and density by bundling actin filaments, distinct from CAII's role in pH buffering.

bioRxiv · Aug 19, 2019Cell Biology