Author

Z. N. Warnken

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:drug response / drug discovery· 3 Organism:mouse· 2 Organism:rat· 2 Research Focus:phylogenetics / evolution· 1

Frequent Co-Authors

R. O. Williams· 4 shared C. Moon· 2 shared D. J. Christensen· 2 shared J. J. Koleng· 2 shared M. O. Jara· 2 shared S. Sahakijpijarn· 2 shared C. Cano· 1 shared E. Maier· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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4 shared papersPharmacology & Toxicology

R. O. Williams

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4 papers

Recent·Most cited

Feasibility of intranasal delivery of thin-film freeze-dried, mucoadhesive AS01B-adjuvanted vaccine powders

Y.-S. Yu, K. AboulFotouh, G. Williams, J. Suman, C. Cano, Z. N. Warnken, R. O. Williams, Z. Cui

This study demonstrates that thin-film freeze-drying can convert a liquid vaccine into a dry powder with mucoadhesive properties, which can be effectively delivered using a nasal device for intranasal vaccination.

bioRxiv · Nov 1, 2022 · PreprintPharmacology & Toxicology

Niclosamide Inhalation Powder Made by Thin-Film Freezing: Pharmacokinetic and Toxicology Studies in Rats and Hamsters

M. O. Jara, Z. N. Warnken, S. Sahakijpijarn, C. Moon, E. Y. Maier, D. J. Christensen, J. J. Koleng, J. I. Peters, S. D. Hackman, R. O. Williams

This paper develops a niclosamide inhalation powder using thin-film freezing and tests its pharmacokinetics and toxicity in rats and hamsters for COVID-19 treatment.

bioRxiv · Jan 26, 2021 · PreprintPharmacology & Toxicology

Amorphous solid dispersions and the confounding effect of nanoparticles in in vitro dissolution and in vivo testing: Niclosamide as a case of study

M. O. Jara, Z. N. Warnken, R. O. Williams

This paper develops an amorphous solid dispersion of niclosamide, achieving increased bioavailability through nanoparticle formation, and validates its performance in vitro and in a rat model.

Pharmaceutics · Jan 14, 2021Peer-reviewedPharmacology & Toxicology

In Vivo Pharmacokinetic Study of Remdesivir Dry Powder for Inhalation in Hamsters

s. sahakijpijarn, C. Moon, Z. N. Warnken, E. Maier, J. E. DeVore, D. J. Christensen, J. J. Koleng, R. O. Williams

This study evaluates the pharmacokinetics of remdesivir dry powder for inhalation in hamsters, showing higher drug levels and suggesting a twice-daily dosing regimen.

bioRxiv · Dec 22, 2020Pharmacology & Toxicology