Author

Y.-S. Yu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2 Cancer Biology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:comparative / phylogenetic analysis· 1 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

C. Cano· 2 shared G. Williams· 2 shared J. Suman· 2 shared K. AboulFotouh· 2 shared R. O. Williams· 2 shared Z. Cui· 2 shared C. J. Winchell· 1 shared D. A. Weisblat· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersPharmacology & Toxicology

C. Cano

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Acceleration of genome rearrangement in clitellate annelids

D. T. Schultz, E. A. C. Heath-Heckman, C. J. Winchell, D.-H. T. Kuo, Y.-s. Yu, F. Oberauer, K. Kocot, S.-J. Cho, O. Simakov, D. A. Weisblat

The paper compares 12 clitellate genomes and 11 outgroup representatives to show that genome rearrangements in Clitellata began at their base and significantly shaped the Hox cluster evolution.

bioRxiv · May 12, 2024 · PreprintEvolutionary Biology

Feasibility of intranasal delivery of thin-film freeze-dried monoclonal antibodies

Y.-S. Yu, H. Xu, K. AboulFotouh, G. Williams, J. Suman, S. Sahakijpijarn, C. Cano, Z. Warnken, K. C.- W. Wu, R. O. Williams, Z. Cui

This paper demonstrates the feasibility of intranasally delivering monoclonal antibodies as dry powders using thin-film freeze-drying and the UDS Powder Nasal Spray System.

bioRxiv · Oct 23, 2023 · PreprintPharmacology & Toxicology

Feasibility of intranasal delivery of thin-film freeze-dried, mucoadhesive AS01B-adjuvanted vaccine powders

Y.-S. Yu, K. AboulFotouh, G. Williams, J. Suman, C. Cano, Z. N. Warnken, R. O. Williams, Z. Cui

This study demonstrates that thin-film freeze-drying can convert a liquid vaccine into a dry powder with mucoadhesive properties, which can be effectively delivered using a nasal device for intranasal vaccination.

bioRxiv · Nov 1, 2022 · PreprintPharmacology & Toxicology

Quantum pBac: An effective, high-capacity piggyBac-based gene integration vector system for unlocking gene therapy potential

W.-K. Hua, J. C. Hsu, Y.-C. Chen, P. S. Chang, K.-L. K. Wen, P.-N. Wang, Y.-S. Yu, Y.-C. Chen, I.-C. Cheng, S. C.-Y. Wu

This paper develops a virus-free gene therapy vector system, Quantum pBac, which improves transposition efficiency and payload capacity for CAR-T cell production.

bioRxiv · Apr 29, 2022Cancer Biology