Author

E. Y. Maier

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

C. Moon· 1 shared C. N. Wilson· 1 shared D. Ghosh· 1 shared D. J. Christensen· 1 shared H. J. Bai· 1 shared H. Li· 1 shared J. E. DeVore· 1 shared J. I. Peters· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperPharmacology & Toxicology

C. Moon

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Electrostatic-driven Interactions Enhance Intratumoral Retention and Antitumor Efficacy of Immune Checkpoint Blockade Antibodies

R. P. Mohanty, Y. Pan, M. M. Lewis, M. R. Soto, E. Y. Maier, R. F. Alzhrani, D. Ghosh

Peptide-conjugated immune checkpoint blockade antibodies show enhanced antitumor efficacy through electrostatic interactions with tumor ECM, increasing CD8+ T cell infiltration and reducing regulatory T cells.

bioRxiv · Dec 22, 2023 · PreprintBioengineering

CRISPR metabolic screen identifies ATM and KEAP1 as targetable genetic vulnerabilities in solid tumors.

H. Li, Y. Liu, C. N. Wilson, H. J. Bai, M. Jones, S. Wang, Y. Xiao, J. E. DeVore, E. Y. Maier, M. Boufraqech, U. Weyemi

The paper identifies ATM and KEAP1 as targetable vulnerabilities in solid tumors through a CRISPR metabolic screen revealing their synthetic lethality.

bioRxiv · May 3, 2022Cancer Biology

Niclosamide Inhalation Powder Made by Thin-Film Freezing: Pharmacokinetic and Toxicology Studies in Rats and Hamsters

M. O. Jara, Z. N. Warnken, S. Sahakijpijarn, C. Moon, E. Y. Maier, D. J. Christensen, J. J. Koleng, J. I. Peters, S. D. Hackman, R. O. Williams

This paper develops a niclosamide inhalation powder using thin-film freezing and tests its pharmacokinetics and toxicity in rats and hamsters for COVID-19 treatment.

bioRxiv · Jan 26, 2021 · PreprintPharmacology & Toxicology