Monotherapy efficacy of BBB-permeable small molecule activators of PP2A in glioblastoma
J. Merisaari, O. V. Denisova, M. Doroszko, V. Le Joncour, P. Johansson, W. P. J. Leenders, D. B. Kastrinsky, Z. Nilesh, G. Narla, P. Laakkonen, S. Nelander, M. Ohlmeyer, J. Westermarck
This study shows that BBB-permeable PP2A activators reduce GB tumor growth and improve survival in mice with diverse GB subtypes.
bioRxiv · Sep 27, 2019 · PreprintCancer Biology