Intratumor Childhood Vaccine-Specific CD4+ T cell Recall Coordinates Antitumor CD8+ T cells and Eosinophils
M. C. Brown, Z. P. McKay, Y. Yang, G. M. Beasley, D. M. Ashley, D. D. Bigner, S. K. Nair, M. Gromeier
This paper shows that childhood vaccines can enhance antitumor immunity by coordinating CD4+ T cells, CD8+ T cells, and eosinophils in mouse models and correlates these effects with human transcriptome data.
bioRxiv · Mar 14, 2022Immunology