BiochemistrybioRxivPreprint
An Unexpected Single-step Glycosylation Enables the Construction of Antibody-Biomacromolecule Conjugates as Therapeutics
Y. Yang, Z. t. Song, T. Tian…·J. P. Li
This paper demonstrates a method to efficiently conjugate biomacromolecules to antibodies using modified Fc glycan and an engineered enzyme, enabling rapid and homogeneous antibody conjugates with therapeutic applications.
DOI 10.1101/2022.09.04.506510