Author

J. P. Li

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Organism:human· 3 Assay:proteomics· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:differential expression· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

Y. Yang· 3 shared M. Chen· 2 shared P. Wu· 2 shared Q. Xue· 2 shared T. Tian· 2 shared Z. Zhao· 2 shared A. S. Jalloh· 1 shared B. Dinner· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersImmunology

Y. Yang

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Anti-PD-1-iRGD Peptide Conjugate Boosts Antitumor Efficacy via Engagement Augmentation and Penetration Enhancement of T cells

Y. Pan, Q. Xue, Y. Yang, T. Shi, H. Wang, X. Song, Y. Luo, B. Liu, Z. Song, J. P. Li, J. Wei

This paper develops a PD-1-iRGD conjugate that enhances antitumor efficacy by improving T cell engagement and penetration, and expands a unique population of CD8+ T cells in the tumor microenvironment.

bioRxiv · Aug 4, 2023 · PreprintImmunology

An Unexpected Single-step Glycosylation Enables the Construction of Antibody-Biomacromolecule Conjugates as Therapeutics

Y. Yang, Z. t. Song, T. Tian, Z. Zhao, J. Chen, J. p. Hu, X. Jiang, G. l. Yang, Q. Xue, X. l. Zhao, W. x. Sha, Y. Yang, J. P. Li

This paper demonstrates a method to efficiently conjugate biomacromolecules to antibodies using modified Fc glycan and an engineered enzyme, enabling rapid and homogeneous antibody conjugates with therapeutic applications.

bioRxiv · Sep 4, 2022 · PreprintBiochemistry

Chemoenzymatic Measurement of Cell-surface Glycan in Single-cell Multiomics: LacNAc as an Example

W. Yu, X. Zhao, A. S. Jalloh, Y. Zhao, B. Dinner, Y. Yang, S. Ouyang, Y. Li, T. Tian, Z. Zhao, R. Yang, M. Chen, G. Lauvau, Z. Guo, P. Wu, J. P. Li

The paper introduces a chemoenzymatic method to detect cell-surface glycan in single-cell multiomics, showing increased LacNAc in activated CD8+ T cells and its correlation with glycolytic activity.

bioRxiv · Sep 1, 2022 · PreprintImmunology

Detecting Tumor Specific Antigen-Reactive T cells from Tumor Infiltrating Lymphocytes via Interaction Dependent Fucosyl-biotinylation

Z. Liu, J. P. Li, M. Chen, M. Wu, Y. Shi, W. Li, J. R. Teijaro, P. Wu

This paper introduces FucoID, a method to detect and isolate tumor-specific antigen-reactive T cells from tumor-infiltrating lymphocytes using fucosyl-biotinylation, revealing distinct gene features and functional capabilities.

bioRxiv · Mar 18, 2020 · PreprintImmunology