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10 papers
Recent·Most cited
M. Li, x. shu, R. Wang, Z. Li, Q. Xue, C. Liu, F. Cheng, H. Zhao, J. Wang, J. Liu, C. Hu, J. Li, S. Ouyang
The paper identifies a CRISPR-repressed toxin that provides population-level immunity against diverse anti-CRISPR elements by expelling them through abortive infection-like effects.
bioRxiv · Jan 5, 2024 · PreprintMicrobiology
Y. Pan, Q. Xue, Y. Yang, T. Shi, H. Wang, X. Song, Y. Luo, B. Liu, Z. Song, J. P. Li, J. Wei
This paper develops a PD-1-iRGD conjugate that enhances antitumor efficacy by improving T cell engagement and penetration, and expands a unique population of CD8+ T cells in the tumor microenvironment.
bioRxiv · Aug 4, 2023 · PreprintImmunology
C. Liu, R. Wang, J. Li, F. Cheng, X. Shu, H. Zhao, Q. Xue, H. Yu, A. Wu, L. Wang, S. Hu, Y. Zhang, J. Yang, H. Xiang, M. Li
The paper shows degenerated CRISPRs encode regulatory RNAs that autoregulate Cas protein expression, balancing immunity and host fitness costs.
bioRxiv · Mar 10, 2023 · PreprintMicrobiology
Y. Yang, Z. t. Song, T. Tian, Z. Zhao, J. Chen, J. p. Hu, X. Jiang, G. l. Yang, Q. Xue, X. l. Zhao, W. x. Sha, Y. Yang, J. P. Li
This paper demonstrates a method to efficiently conjugate biomacromolecules to antibodies using modified Fc glycan and an engineered enzyme, enabling rapid and homogeneous antibody conjugates with therapeutic applications.
bioRxiv · Sep 4, 2022 · PreprintBiochemistry
D. Zhao, S. Zhang, S. Kumar, H. Zhou, Q. Xue, W. Sun, J. Zhou, H. Xiang
This paper identifies a new family of 'Ca. Nanohaloarchaeota' from hypersaline environments, showing they are an intermediate stage in the evolution of symbiosis with Halobacteria.
bioRxiv · May 20, 2022Microbiology
Q. Xue, S. R. S. Varady, T. Q. A. Waddell, J. Carrington, M. Roh-Johnson
This study compares Paxillin phosphorylation regulation in vivo and in vitro during cell migration, finding differential effects on cell movement in zebrafish and mouse models.
bioRxiv · Mar 2, 2022 · PreprintCell Biology
J. Pan, L. Yang, Y. Deng, B. Sun, L. Zhang, W. Wu, J. Li, H. Cheng, Y. Li, W. Xu, J. Yang, Y. Sun, H. Fei, Q. Xue, Y. Zhou, , H. Ma
The paper identifies non-reproducible antibody-antigen interactions in clinical sera and develops a model to explain them, improving serological testing for viral infections like COVID-19.
bioRxiv · Jul 20, 2021 · PreprintImmunology
Q. Wang, B. Cheng, Q. Xue, Q. Gao, A. Huang, K. Wang, N. Tang
This study shows GSTZ1 enhances sorafenib-induced ferroptosis in HCC by inhibiting the NRF2/GPX4 axis, and its deficiency leads to resistance to sorafenib.
bioRxiv · Dec 14, 2020Cancer Biology
W. Jiang, J. H. Rasmussen, Q. Xue, M. Ding, X. Zheng, C. P. Elemans
The paper develops and validates a high-fidelity 3D continuum model for avian voiced sound production, showing it accurately predicts vibratory and acoustic traits.
bioRxiv · Oct 10, 2019Zoology
Q. Xue, H. Xu, H. Liu, J. Pan, J. Yang, M. Sun, Y. Chen, W. Xu, H. Ma, X. Cai
The paper develops a DIVA strategy using epitope-containing short peptides (ECSPs) to differentiate vaccinated from infected animals, showing distinct IgG serodynamics that enable effective monitoring.
bioRxiv · Sep 5, 2019Immunology