In Vivo CRISPR Screens Identify E3 Ligase Cop1 as a Modulator of Macrophage Infiltration and Cancer Immunotherapy Target
X. Wang, C. Tokheim, B. Wang, S. S. Gu, Q. Tang, Y. Li, N. Traugh, Y. Zhang, Z. W. Li, B. Zhang, J. Fu, T. Xiao, W. Li, C. A. Meyer, J. Chu, , X. S. Liu
The paper identifies Cop1 as a modulator of macrophage infiltration and cancer immunotherapy in TNBC by using in vivo CRISPR screens and multi-omics analyses.
bioRxiv · Dec 9, 2020Cancer Biology