Loss Of PTEN Promotes Formation Of Signaling-Capable Clathrin-Coated Pits
L. K. Rosselli-Murai, J. A. Yates, S. Yoshida, J. T. Bourg, K. K. Y. Ho, M. White, J. Prisby, X. Tan, M. Altemus, L. Bao, Z.-F. Wu, S. L. Veatch, J. A. Swanson, S. D. Merajver, A. P. Liu
This study shows PTEN regulates clathrin-coated pit dynamics by modulating PI(3,4,5)P3 levels, promoting short-lived signaling-capable CCPs in cancer cells.
bioRxiv · Jul 28, 2017Cell Biology