Author

J. A. Yates

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Bioengineering· 1 Cell Biology· 1 Ecology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:drug response / drug discovery· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:ecology & biodiversity· 1

Frequent Co-Authors

S. D. Merajver· 4 shared A. K. Mapp· 2 shared L. Bao· 2 shared Y. Liu· 2 shared A. C. Little· 1 shared A. O. Bergland· 1 shared A. P. Liu· 1 shared A. Peiffer· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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4 shared papersBiochemistry

S. D. Merajver

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Author profile →

5 papers

Recent·Most cited

Inhibition of CREB binding and function with a dual-targeting ligand

Y. Liu, S. T. Joy, M. J. Henley, J. A. Yates, S. D. Merajver, A. K. Mapp

This study develops a dual-targeting ligand, CREBLL-tide, that inhibits the KIX-CREB PPI with high potency and selectivity, showing anti-proliferation activity in breast cancer cells.

bioRxiv · Sep 3, 2023Biochemistry

Spatial and temporal variation in abundance of introduced African fig fly (Zaprionus indianus) (Diptera: Drosophilidae) in the eastern United States

L. M. Rakes, M. Delamont, C. Cole, J. A. Yates, L. J. Blevins, F. N. Hassan, A. O. Bergland, P. A. Erickson

This study examines the spatial and temporal variation in the abundance of the invasive African fig fly Zaprionus indianus in the eastern United States, showing its susceptibility to cold and the need for systematic sampling.

bioRxiv · Mar 24, 2023 · PreprintEcology

Norstictic acid is a selective allosteric transcriptional regulator

J. M. Garlick, S. M. Sturlis, P. A. Bruno, J. A. Yates, A. Peiffer, Y. Liu, L. Goo, L. Bao, S. De Salle, G. Tamayo-Castillo, C. L. Brooks, S. D. Merajver, A. K. Mapp

This study identifies norstictic acid as a selective allosteric inhibitor of Med25-mediated transcriptional interactions, showing its effect in vitro and in a breast cancer model.

bioRxiv · Mar 26, 2021Biochemistry

Development of a high-throughput radial migration device

C. R. Oliver, A. C. Little, T. M. Westerhof, P. Pathanjeli, J. A. Yates, S. D. Merajver

This paper develops a high-throughput radial migration device for measuring cell migration, enabling therapeutic screening and phenotypic response analysis.

bioRxiv · Jan 31, 2020 · PreprintBioengineering

Loss Of PTEN Promotes Formation Of Signaling-Capable Clathrin-Coated Pits

L. K. Rosselli-Murai, J. A. Yates, S. Yoshida, J. T. Bourg, K. K. Y. Ho, M. White, J. Prisby, X. Tan, M. Altemus, L. Bao, Z.-F. Wu, S. L. Veatch, J. A. Swanson, S. D. Merajver, A. P. Liu

This study shows PTEN regulates clathrin-coated pit dynamics by modulating PI(3,4,5)P3 levels, promoting short-lived signaling-capable CCPs in cancer cells.

bioRxiv · Jul 28, 2017Cell Biology