Author

Zachary Apell

University of Michigan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Assay:ATAC-seq· 2 Assay:CUT&Tag· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:ChIP-seq· 1 Research Focus:deconvolution· 1 Research Focus:dimensionality reduction· 1 Approach:experimental assay· 1

Frequent Co-Authors

Minji KimiD· 2 shared Alan P. BoyleiD· 1 shared Alexander VargoiD· 1 shared Bluma J. LeschiD· 1 shared Bradley Robert CairnsiD· 1 shared Jun Z. LiiD· 1 shared Lindsay MoritziD· 1 shared Lydia FreddolinoiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersGenomics

Minji KimORCID

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2 papers

Recent·Most cited

3D chromatin compartment of round spermatids encodes the spatiotemporal program of histone-to-protamine exchange in spermiogenesis

Mashiat Rabbani, Zachary Apell, Timothy J. Parnell, Lindsay Moritz, Sion Kim, Sowmya Srinivasan, Ritvija Agrawal, Alexander Vargo, Peter Orchard, Wenxin Xie, Lydia Freddolino, Alan P. Boyle, Jun Z. Li, Bluma J. Lesch, Bradley Robert Cairns, , Saher Sue Hammoud

The paper defines a 3D chromatin compartment blueprint that programs histone-to-protamine exchange during spermiogenesis using ATAC-seq, CUT&Tag, and Hi-C.

bioRxiv · Mar 12, 2026 · PreprintGenomics

Chrom-Sig: de-noising 1-dimensional genomic profiles by signal processing methods

N. Gupta, Zachary Apell, Minji Kim

Chrom-Sig de-noises 1-dimensional genomic coverage tracks using signal processing to separate signal from noise, validated across multiple datasets.

Bioinformatics · Nov 27, 2025Peer-reviewedBioinformatics