Regulation of polyamine interconversion enzymes affects α-Synuclein levels and toxicity in a Drosophila model of Parkinsons disease
Bedri Ranxhi, Zoya R. Bangash, Zachary M. Chbihi, Zaina Qadri, Nazin N. Islam, Sokol V. Todi, Peter A. LeWitt, Wei‐Ling Tsou
This study shows that manipulating polyamine interconversion enzymes in a Drosophila Parkinson's model affects alpha-synuclein levels and toxicity, suggesting a potential therapeutic target.
npj Parkinson s Disease · Aug 6, 2025Peer-reviewedNeuroscience