Functionally Mature Bioengineered Human Skeletal Muscle Tissues Capture Essential Aspects of Glucose Metabolism
Carlos Henríquez‐Olguín, Martina Kubec Højfeldt, Christopher T. A. Lewis, Jesper B. Birk, Tianfang Wang, Zelin Li, Pia Jensen, Pauline Blomquist, Bo F. Hansen, Roberto Meneses‐Valdés, Enrique M. Toledo, Jeb Hogan, Zhe Wang, Charis‐Patricia Segeritz, Jørgen F. P. Wojtaszewski, , Jonas R. Knudsen
This study develops bioengineered human skeletal muscle tissues that mature metabolically and functionally, capturing key aspects of glucose metabolism and response to exercise and pharmacological agents.
bioRxiv · Jan 16, 2026 · PreprintCell Biology