Author

Zhen-Yuan Lin

Mount Sinai Hospital

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Anne‐Claude GingrasiD· 1 shared Antonio MollicaiD· 1 shared Cassandra J. WongiD· 1 shared Edith Cheng· 1 shared Eric I. CamposiD· 1 shared Grant W. BrowniD· 1 shared Michael W. FergusoniD· 1 shared Shahir M. MorcosiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Anne‐Claude GingrasORCID

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1 paper

Recent·Most cited

PRMT1 arginine methylation of MCM4 restricts ssDNA gap formation during DNA replication

Michael W. Ferguson, Cassandra J. Wong, Xiaohan Yang, Edith Cheng, Antonio Mollica, Shahir M. Morcos, Wade H. Dunham, Zhen-Yuan Lin, Eric I. Campos, Anne‐Claude Gingras, Grant W. Brown

This study identifies PRMT1 as a replisome-associated methyltransferase that suppresses ssDNA gap formation by methylating MCM4, thereby maintaining fork integrity during DNA replication.

bioRxiv · Jun 4, 2026 · PreprintMolecular Biology