Human ribosomes interactions reveal the binding landscape of neomycin
Meng Wu, Lingfan Zhu, Changfeng Jia, Xinyi Zhang, Zhongcheng Zhao, Hanhan Liu, Chuansen Yi, Shuangli Sun, Ke Liu, Zhe Zhang, Lei Guo, Xuben Hou, Wen‐Fei Li
The paper investigates neomycin's binding to human ribosomes using Cryo-EM and functional assays, revealing structural binding patterns that differ from cellular observations.
bioRxiv · Jul 22, 2025 · PreprintBiochemistry