Exploration of oncogenic cooperation between germline variation and somatic mutation in prostate cancer progression
Zuzanna Kolodynska, Kimberley M. Hanssen, Florian H. Geyer…·Thomas G. P. Grünewald
This study identifies PTPRK as a gene modulated by TMPRSS2::ERG fusion and a regulatory SNP, showing its role in prostate cancer progression and potential as a biomarker.