Author

Dimitris Nastos

Alexander Fleming Biomedical Sciences Research Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Katerina M. AntoniouiD· 2 shared Pantelis HatzisiD· 2 shared Paraskevi KanellopoulouiD· 2 shared Vassilis AidinisiD· 2 shared Alexios N. MatralisiD· 1 shared Antreas AfantitisiD· 1 shared Apostolos GalarisiD· 1 shared Argyrios TzouvelekisiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersPathology

Katerina M. AntoniouORCID

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2 papers

Recent·Most cited

An aerosolised dual-action Autotaxin inhibitor- PPARγ agonist for the treatment of pulmonary fibrosis

Alexios N. Matralis, Elli-Anna Stylianaki, Eleni M. Ladopoulou, Paraskevi Kanellopoulou, Stefanos Smyrniotis, Christiana Magkrioti, Konstantinos D. Papavasileiou, Sabine Willems, Juan Pablo Rincon Pabon, Dimitris Nastos, Αλέξανδρος Γαλάρας, Skarlatos Dedos, Eleanna Kaffe, Pantelis Hatzis, Daniel Merk, , Vassilis Aidinis

This paper introduces EL244, a dual ATX inhibitor and PPARγ agonist for treating pulmonary fibrosis, showing reduced LPA levels and fibrosis in a bleomycin model.

bioRxiv · Nov 12, 2025 · PreprintPathology

SRC-mediated and TKS5-enabled podosome formation is an inherent property of IPF fibroblasts, promoting ECM invasion and pulmonary fibrosis

Ilianna Barbayianni, Paraskevi Kanellopoulou, Dionysiοs Fanidis, Eleftheria-Dimitra Ntouskou, Dimitris Nastos, Apostolos Galaris, Vaggelis Harokopos, Pantelis Hatzis, Eliza Tsitoura, Robert Homer, Naftali Kaminski, Katerina M. Antoniou, Bruno Crestani, Argyrios Tzouvelekis, Vassilis Aidinis

This study identifies TKS5-mediated podosome formation in IPF fibroblasts as a driver of ECM invasion and pulmonary fibrosis, with potential therapeutic targeting via src kinase inhibition.

bioRxiv · Jan 25, 2023 · PreprintMolecular Biology