Author

Ann E. Tollefson

Saint Louis UniversityORCID 0000-0001-5010-3241Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 2

Frequent Co-Authors

Anna Cline-SmithiD· 2 shared Károly TóthiD· 2 shared B. A. KashemiroviD· 1 shared Caroll B. Hartline· 1 shared Charles E. McKennaiD· 1 shared Charlotte Quentin-FroignantiD· 1 shared Franck GallardoiD· 1 shared Harald WodrichiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersMicrobiology

Anna Cline-SmithORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintFeb 20, 2025

LAVR-289, a New Orally Bioavailable Inhibitor of Adenovirus Replication in vitro and in vivo.

Charlotte Quentin-Froignant, Ann E. Tollefson, Anna Cline-Smith…·Franck Gallardo

This study evaluates LAVR-289, an acyclonucleoside phosphonate, showing potent antiviral activity against adenovirus in vitro and in vivo, with 100% survival in immunocompromised hamsters.

DOI 10.1101/2025.02.20.639236

mouseexperimental assay

𝕏 PostBluesky

BiochemistrybioRxivPreprintNov 1, 2024

Synthesis of USC-093 and comparison with its promoiety enantiomer USC-093D against adenovirus in vitro and in a Syrian hamster model

Jiayi Yang, Samantha B. Riemann, Jinglei Lyu…·Charles E. McKenna

This paper synthesizes USC-093 and its enantiomer USC-093D, comparing their antiviral efficacy against adenovirus in vitro and in a Syrian hamster model, finding no significant improvement in vivo from the D-enantiomer.

1 citation

mouseexperimental assay

𝕏 PostBluesky