BiochemistrybioRxivPreprint
Synthesis of USC-093 and comparison with its promoiety enantiomer USC-093D against adenovirus in vitro and in a Syrian hamster model
Jiayi Yang, Samantha B. Riemann, Jinglei Lyu…·Charles E. McKenna
This paper synthesizes USC-093 and its enantiomer USC-093D, comparing their antiviral efficacy against adenovirus in vitro and in a Syrian hamster model, finding no significant improvement in vivo from the D-enantiomer.
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