Jin Jiang

The paper shows that Numb acts alongside BMP signaling to ensure robust intestinal stem cell self-renewal in Drosophila midgut, particularly when BMP signaling is compromised.

This study shows phosphorylation-induced SUMOylation of Ulk4 promotes its condensation at the ciliary tip, facilitating Hedgehog signal transduction by recruiting Stk36 and Gli2.

This study shows YAP inhibits NF-κB signaling and ccRCC growth by blocking ZHX2, a co-factor of NF-κB, and competes with ZHX2 for binding to p65.

This study identifies Ulk4's role in promoting Shh signaling by regulating Stk36 localization and Gli2 phosphorylation at the ciliary tip.