Catherine G. Dulac

The paper identifies hormone-specific neuronal circuits in the hypothalamus that regulate sex- and state-dependent infant caregiving behaviors in mothers and fathers.

The paper investigates pathogen-specific sickness states by analyzing immune and neural responses across multiple scales in various inflammatory models.

The paper identifies a specific neuronal population in the central amygdala that promotes suckling and early postnatal growth in mice.

The paper identifies two distinct serotonin neuron populations that regulate pup care behavior in female mice, showing how they switch function across reproductive stages.

The paper maps molecular and spatial organization of the mouse primary olfactory system in response to social odors using MERFISH and identifies spatial domains of sensory responses.

The paper examines how sensory input, sex, and function influence the developmental trajectories of hypothalamic cell types during early life transitions.

Opposing glutamatergic MPN Isolation and mostly GABAergic MPN Reunion neurons in the mouse preoptic hypothalamus encode social need and satiety, with touch as a likely cue.

This paper introduces a 3D MERFISH method for imaging thick tissues, demonstrating its application on mouse brain sections with high accuracy.

The paper develops a platform combining imaging and sequencing to study genetic perturbations in mouse liver, identifying regulators of hepatocyte zonation and liver unfolded protein response.

This study maps age-related changes in mouse brain cellular and molecular organization using spatial transcriptomics, revealing significant shifts in non-neuronal cells and glial activation patterns.

The paper uses spatially resolved single-cell transcriptomics to map transcriptional heterogeneity and spatial organization of cell types in the periaqueductal gray during instinctive behaviors.

This study identifies PeFAUcn3 neurons as a circuit controlling infant-directed neglect and aggression by linking their activation to specific behavioral responses.

The paper introduces tools to evaluate single-cell clustering stability using subsampling and the Jaccard similarity index, with an R package and Snakemake workflow for implementation.

The paper identifies a cortico-thalamic circuit in mice that supports social hierarchy through molecular and biophysical plasticity.

This study shows that oxytocin signaling in the medial amygdala is essential for male mice to discriminate female social cues.